Factor XIII (FXIII) deficiency is an extremely rare bleeding disorder with an
approximately 12-times higher than the rest of the world. The
International Society for Thrombosis and Hemostasis (ISTH) suggested a
standard algorithm for precise diagnosis and classification of FXIII
deficiency (FXIIID). However, due to lack of investment in proper
equipment and procedures in Iran, almost no part of this algorithm can
be used to diagnose Iranian patients. Thus, this study proposes
a guideline for accurate molecular and laboratory diagnosis of FXIIID
based on the available tools. Because this study suggests a simple and
reliable algorithm for early diagnosis, it can therefore, reduce the rates of
morbidity and mortality of FXIIID patients with this condition.
دریافت
